John W Newman Selected Research

Oxylipins

2/2022	Plasma Oxylipin Profile Discriminates Ethnicities in Subjects with Non-Alcoholic Steatohepatitis: An Exploratory Analysis.
10/2021	Oxylipin responses to fasting and insulin infusion in a large mammalian model of fasting-induced insulin resistance, the northern elephant seal.
1/2021	Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification.
1/2021	Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer's disease.
1/2021	Effects of inflammation and soluble epoxide hydrolase inhibition on oxylipin composition of very low-density lipoproteins in isolated perfused rat livers.
9/2020	Linoleic Acid-Rich Oil Supplementation Increases Total and High-Molecular-Weight Adiponectin and Alters Plasma Oxylipins in Postmenopausal Women with Metabolic Syndrome.
1/2020	Mid-gestation serum lipidomic profile associations with spontaneous preterm birth are influenced by body mass index.
1/2020	α-Linolenic acid-enriched butter attenuated high fat diet-induced insulin resistance and inflammation by promoting bioconversion of n-3 PUFA and subsequent oxylipin formation.
1/2020	Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids.
1/2020	Impact of a weight loss and fitness intervention on exercise-associated plasma oxylipin patterns in obese, insulin-resistant, sedentary women.

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John W Newman Research Topics

Disease

30	Inflammation (Inflammations) 07/2022 - 05/2002
18	Insulin Resistance 01/2022 - 06/2009
13	Obesity 07/2022 - 08/2004
9	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 05/2004
8	Body Weight (Weight, Body) 01/2018 - 08/2004
7	Overweight 01/2022 - 02/2010
7	Weight Loss (Weight Reduction) 01/2020 - 08/2013
6	Type 2 Diabetes Mellitus (MODY) 09/2020 - 08/2004
5	Atherosclerosis 01/2019 - 02/2006
5	Hypertension (High Blood Pressure) 01/2009 - 05/2004
4	Dyslipidemias (Dyslipidemia) 01/2020 - 12/2008
3	Non-alcoholic Fatty Liver Disease 02/2022 - 01/2012
3	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 11/2008
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2020 - 01/2014
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 02/2013 - 04/2012
3	Leukemia 02/2013 - 04/2012
2	Hyperemia 01/2022 - 12/2015
2	Ischemia 01/2020 - 08/2006
2	Atopic Dermatitis (Atopic Eczema) 01/2018 - 01/2017
2	Weight Gain 05/2017 - 01/2016
2	Chronic Disease (Chronic Diseases) 01/2017 - 11/2016
2	Infections 01/2017 - 01/2016
2	Glucose Intolerance 06/2014 - 01/2014
2	Stroke (Strokes) 04/2011 - 12/2005
2	Proteinuria 08/2007 - 05/2005
2	Nephrotic Syndrome (Syndrome, Nephrotic) 08/2007 - 05/2005
2	Membranous Glomerulonephritis (Membranous Nephropathy) 08/2007 - 05/2005
2	Albuminuria 05/2005 - 08/2004
1	Alcoholic Fatty Liver 02/2022
1	Hypertriglyceridemia 01/2022
1	Tuberculosis (Tuberculoses) 01/2022
1	Cognitive Dysfunction 01/2021
1	Thrombosis (Thrombus) 01/2021
1	Neuroinflammatory Diseases 01/2021
1	Hypoxia (Hypoxemia) 01/2021

Drug/Important Bio-Agent (IBA)

26	LipidsIBA 07/2022 - 01/2005
23	OxylipinsIBA 02/2022 - 12/2008
15	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 05/2002
14	Insulin (Novolin)FDA Link 10/2021 - 06/2009
10	EndocannabinoidsIBA 02/2022 - 01/2012
10	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 02/2022 - 11/2009
10	Epoxide HydrolasesIBA 01/2021 - 05/2002
8	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2022 - 05/2011
8	Triglycerides (Triacylglycerol)IBA 01/2022 - 05/2005
7	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2014
7	AcidsIBA 01/2021 - 12/2003
6	Biomarkers (Surrogate Marker)IBA 01/2021 - 10/2011
6	Bile Acids and Salts (Bile Acids)IBA 01/2021 - 01/2014
5	Epoxy Compounds (Epoxides)IBA 01/2020 - 05/2002
5	Proteins (Proteins, Gene)FDA Link 10/2019 - 08/2004
5	Lipoproteins (Lipoprotein)IBA 01/2019 - 05/2005
4	Nonesterified Fatty Acids (NEFA)IBA 01/2021 - 01/2012
4	CeramidesIBA 01/2020 - 12/2014
4	Arachidonic Acid (Vitamin F)IBA 01/2020 - 09/2005
4	EicosanoidsIBA 11/2019 - 11/2009
3	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2021 - 12/2003
3	Docosahexaenoic AcidsIBA 01/2021 - 03/2014
3	alpha-Linolenic Acid (Linolenic Acid)IBA 01/2021 - 01/2020
3	Linoleic Acid (Linoleate)IBA 09/2020 - 01/2017
3	EnzymesIBA 01/2018 - 12/2003
3	Vincristine (Oncovin)FDA LinkGeneric 02/2013 - 04/2012
2	lipoxin A4IBA 07/2022 - 12/2015
2	Lys(8)- oxytocin (OXL)IBA 02/2022 - 01/2020
2	Sucrose (Saccharose)IBA 01/2022 - 06/2014
2	Hormones (Hormone)IBA 01/2021 - 01/2021
2	CalciumIBA 01/2021 - 01/2014
2	Eicosapentaenoic AcidIBA 01/2021 - 03/2014
2	Dinoprostone (PGE2)FDA Link 01/2021 - 01/2016
2	SteroidsIBA 01/2021 - 01/2021
2	Cholesterol Esters (Cholesteryl Esters)IBA 01/2020 - 01/2020
2	SphingomyelinsIBA 01/2020 - 12/2014
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2020 - 01/2018
2	zinc-binding protein (zinc binding protein)IBA 01/2018 - 01/2016
2	acylcarnitineIBA 01/2017 - 06/2009
2	Trans Fatty AcidsIBA 01/2017 - 10/2011
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 12/2014 - 08/2004
2	Messenger RNA (mRNA)IBA 01/2014 - 04/2011
2	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 02/2013 - 04/2012
2	ResveratrolIBA 12/2012 - 04/2012
2	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 08/2012 - 05/2011
2	Pharmaceutical PreparationsIBA 02/2010 - 02/2006
2	AlbuminsIBA 01/2009 - 05/2005
2	SaltsIBA 01/2009 - 10/2005
2	ApolipoproteinsIBA 08/2007 - 05/2005
2	AngiotensinsIBA 10/2005 - 05/2004
1	C-Reactive ProteinIBA 07/2022
1	LipoxinsIBA 07/2022
1	Indicators and Reagents (Reagents)IBA 01/2022
1	Egg ProteinsIBA 01/2022
1	Palm OilIBA 01/2022
1	trimethyloxamine (trimethylamine N-oxide)IBA 01/2022
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2021
1	Choline (Choline Chloride)IBA 01/2021
1	docosapentaenoic acidIBA 01/2021
1	prostaglandin E3 (PGE3)IBA 01/2021
1	VLDL LipoproteinsIBA 01/2021
1	Oleic Acid (Oleate)IBA 09/2020
1	AdiponectinIBA 09/2020
1	AdipokinesIBA 09/2020

Therapy/Procedure

2	Fat-Restricted Diet (Diet, Fat Restricted) 10/2017 - 04/2009